DEPARTMENT OF BIOCHEMISTRY|
The Department of biochemistry in Government Sivagangai Medical College and Hospital started functioning from 2011 – 2012 academic year onwards.
NON TEACHING STAFF:
DEMONSTRATION ROOMS:There are 2 rooms which can provide accomodation for 60 students with OHP facility
PRACTICAL CLASS ROOM LABORATORY: There is a practical class laboratory which can provide accomodation for 60 students
RESEARCH LABORATORY: The department has an air conditioned and well equipped laboratory with internet facility
LIBRARY: The department has a library with journals & 120 books covering various sub sections of Biochemistry.
The Tamil Nadu DR. M.G.R Medical University, Chennai.
Biochemistry includes Medical Physics and Molecular Biology. The broad goal of the teaching under-graduate students in bio-chemistry is to make them understand the scientific basis of the life processes at the molecular level and to orient them towards the application of the knowledge acquired in solving clinical problems.
At the end of the course, the student shall be able to:
- Describe the molecular and functional organisation of a cell and lies its subcellular components;
- Delineate structure, function and inter-relationship of biomolecules and consequences of deviation from normal;
- Summarize the fundamental aspects of enzymology and clinical application where in regulation of enzymatic activity is altered.
- Describe digestion and assimilation of nutrients and consequently or malnutrition consequences of malnutrition;
- Integrate the various aspects of metabolism and their regulatory pathways;
- Explain the biochemical basis of inherited disorders with their associated sequelae;
- Describe mechanisms involved in maintenance body fluid and pH homeostasis;
- Outline the molecular mechanisms of gene, expression and regulation the principles of genetic engineering and their application in medicine.
- Summarize molecular concept of body defences and their application in medicine.
- Outline the biochemical basis of environmental health hazards, biochemical basis of cancer and carcinogenesis;
- Familiarize with the principles of various conventional and specialisedlaboratory investigations and instrumentation analysis and interpretation of a given data.
- Suggest experiments to support theoretical concepts and clinical diagnosis.
- Make use of conventional techniques/instruments to perform biochemical analysis relevant to clinical screening and diagnosis.
- Analyze and interpret investigative data.
- Demonstrate the skills of solving scientific and clinical problems and decisionmaking. The knowledge acquired in biochemistry shall help the students to integrate molecular events with structure and function of the human body in health and disease.
- The 100 students study Bio chemistry for a period of one year during 1st yearof M.B.B.S. are divided into 2 batches. Theory and practical classes are conducted by all teaching faculty of the department. As per norms laid down by Medical Council of India ,240 hours are allocated in the first M.B.B.S. to teach biochemistry to students
- Three hours per week is allotted to theory classes for the entire batch and 4 hours for practical to each batch
- Seminars and group discussions involving participation of students are conducted every month
- Periodic Internal Assessment tests both in theory & practicals and viva voce are conducted. A minimum of 5 - 6 internal assessment tests are conducted through out the year
- A model theory & practical examination is conducted prior to the university examination in the month of July
- The academic progress and attendance detail of each student is communicated to the parents in the months of December and June every year.
University Examination details
- Molecular and functional organisation of the cell and its subcelular components.
- Chemistry, Digestion and absorption of carbohydrates, Metabolism of Carbohydrates and disorders of carbohydrate metabolism.
- Chemistry, Digestion and absorption of lipids, Metabolism of lipids and disorders of lipid metabolism.
- Electron transport chain and Biological oxidation.
- Citric acid Cycle and Metabolic integration.
- Heme synthesis, Porphyrins, hemoglobin and metabolism of Bilirubin.
- Chemistry, Digestion, absorption and metabolism of proteins, inborn errors in Protein
- Chemistry of purines, metabolism of Purines, Hyperuricemias.
- Molecular Biology.
- Maintenance of Fluid and Electrolytes.
- Maintenance of pH and acid base disorders.
- Xenobiotics and cancer chemistry.
- Hormones. 9. Laboratory instrumentation, investigation and interpretation
- Out of 100 students in 2012 – 2013 academic year 98% passed out with achieving 3 HONOURS (80% and above) and 22 DISTINCTIONS ( 75% to 80%).
A modern clinical biochemistry laboratory with automated analysers functions round the clock . The samples from out patients are collected in central sample collection area from 8 00 A.M to 1.00 P.M on all days. In addition samples are received from various in-patient wards round the clock. On an average more than samples are processed 200 per day and more than 600 tests are performed everyday.
The department offers all routine biochemical investigations as well as special tests required for the diagnosis and treatment of the patients of Government General Hospital. Special investigations like electrophoresis, chromatography are done in the Special investigations Lab in the College on working days .
An inner view of the Clinical Biochemistry Laboratory with auto analyser facility
Routine Biochemistry Investigations
- Plasma Glucose
- Serum Urea
- Serum Creatinine
- Lipid Profile
- Serum Cholesterol
- Serum Triglyceride
- Serum AST (SGOT)
- Serum ALT (SGPT)
- Serum ALP (Alkaline Phosphatase)
- Serum Amylase
- Ascitic fluid Amylase
- Serum Total Protein
- CSF Protein
- 24 hour Urinary Protein
- Serum CK
- Serum / urine Uric acid
- Serum / Urine Calcium
- Serum / Urine Phosphorus
- Serum / Urine Sodium
- Serum / Urine Potassium
- Arterial Blood Gas Analysis
- Creatinine clearance
- Glucose Tolerance Test
- Thyroid profile tests
Special Biochemistry Investigations
- Serum Protein Electrophoresis
- Urine screening tests for inborn Errors of Metabolism (Qualitative)
- Urine Bence Jones Protein (Qualitative)
- Urine Porphobilinogen (Qualitative)
Evaluation of subclinical anemia using serum ferritin level in rural antenatal mothers- Dr Preethi, Final Year MBBS
1. Thyroid status of adult South Indian population suffering from Chronic Kidney Disease with and without complications and associated risk factors.
Hareesh A (II MBBS), Dr Sangeetha B (Professor, Biochemistry)